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Figure 2 | Journal of Translational Medicine

Figure 2

From: The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

Figure 2

Effects of eplerenone on urinary log10 Na+/K+ in humans. Eplerenone elicited a dose-dependent increase in urinary Na+/K+ in humans. Points represent observed effect in individual subjects. The solid line represents the predicted time course of the effect derived from the indirect response model described in the methods section.

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