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Table 2 Bisphosphonates relative anti-resorptive potency, clinical dosage, and route of administration.

From: Tumour macrophages as potential targets of bisphosphonates

Bisphosphonate Potency Clinical Dose Route Ref.
Etidronate 1   Oral, IV [59]
Clodronate 10 1600 mg/day Oral [59, 60]
Pamidronate 100 90 mg. 3-4 weeks IV [59, 94]
Alendronate 1000 10 mg/kg oral. 1 mg/kg I.V) Oral [59, 62]
Ibandronate 1,000 - 10,000 6 mg 3-4 weeks IV [59]
Risedronate 1,000-10,000 30 mg/d Oral [59]
Zoledronic acid 100,000 4 mg/2-3 weeks IV [3, 59, 95, 96]