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Table 2 Bisphosphonates relative anti-resorptive potency, clinical dosage, and route of administration.

From: Tumour macrophages as potential targets of bisphosphonates

Bisphosphonate

Potency

Clinical Dose

Route

Ref.

Etidronate

1

 

Oral, IV

[59]

Clodronate

10

1600 mg/day

Oral

[59, 60]

Pamidronate

100

90 mg. 3-4 weeks

IV

[59, 94]

Alendronate

1000

10 mg/kg oral. 1 mg/kg I.V)

Oral

[59, 62]

Ibandronate

1,000 - 10,000

6 mg 3-4 weeks

IV

[59]

Risedronate

1,000-10,000

30 mg/d

Oral

[59]

Zoledronic acid

100,000

4 mg/2-3 weeks

IV

[3, 59, 95, 96]

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Journal of Translational Medicine

ISSN: 1479-5876

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