Table 1 Viral distribution in tumor bearing and non-tumor bearing mice 14 dpi
From: Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies
pfu/g tissue | fluorescence | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
mouse # | tumor | blood | ovaries | spleen | kidneys | liver | lung | brain | paw | 4-MU | fluorescein |
1 | NA | ND | ND | ND | ND | ND | ND | ND | 2.10E+06 | 8599 | 1179 |
2 | NA | ND | 2500 | ND | ND | ND | ND | 100 | ND | 4418 | 607 |
3 | NA | ND | 5300 | ND | ND | ND | ND | 20 | ND | 6775 | 855 |
4 | NA | ND | 12000 | ND | 100 | ND | ND | ND | 5.00E+05 | 14587 | 2641 |
5 | NA | ND | 8800 | ND | ND | 100 | ND | ND | ND | 4325 | 483 |
6 | NA | ND | ND | ND | ND | 0 | ND | ND | ND | 5272 | 667 |
7 | 2.70E+07 | ND | ND | 40 | ND | ND | 20 | ND | ND | 40812 | 168977 |
8 | 5.15E+07 | ND | ND | 100 | ND | ND | ND | ND | ND | 43732 | 61137 |
9 | 2.65E+07 | ND | ND | ND | 100 | ND | ND | ND | ND | 43866 | 43572 |
10 | 9.00E+06 | ND | 20 | 20 | 100 | ND | 80 | ND | ND | 38449 | 135454 |
11 | 8.50E+06 | ND | ND | ND | 20 | ND | ND | ND | ND | 41645 | 28754 |