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Table 3 Multivariate analysis of factors contributing to overall survival and disease-free survival in HCC patients

From: Identification of MACC1 as a novel prognostic marker in hepatocellular carcinoma

Variable

Overall survival

Disease-free survival

 

HR (95% CI)

P value

HR (95% CI)

P value

Tumour size

3.008 (1.315-6.881)

0.009

3.227 (1.664-6.260)

0.001

Multiple tumours

1.361 (0.614-3.017)

0.447

2.254 (1.175-4.326)

0.014

Vascular invasion

2.280 (1.140-4.561)

0.020

1.873 (1.002-3.545)

0.049

HBsAg status

-

-

2.922 (1.153-7.403)

0.024

Edmondson-Steiner grade

1.853 (1.016-3.379)

0.044

1.615 (0.964-2.705)

0.068

TNM stage

1.136 (0.650-1.985)

0.654

0.865 (0.546-1.369)

0.535

MACC1 expression level

2.230 (1.257-3.957)

0.006

1.687 (1.034-2.751)

0.036

  1. MACC1, metastasis-associated in colon cancer-1; HCC, hepatocellular carcinoma; HBsAg, hepatitis B surface antigen; HR, hazard ratio; CI, confidence interval.