Skip to main content

Table 3 Multivariable proportional hazards models of risk of biochemical recurrence after prostatectomy associated with prostatectomy Gleason score and individual CTAs*

From: Cancer/Testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy

Variable

HR (95% CI)

P Value

CEP55

  

   CEP55

1.85 (0.76, 4.53)

0.177

   Prostatectomy Gleason score

  

≤ 6

1.0

ref

7 (3 + 4)

22.07 (2.82, 172.74)

0.003

7 (4 + 3)

28.90 (3.34, 250.28)

0.002

8 to 10

29.25 (3.82, 224.08)

0.001

NUF2

  

   NUF2

1.73 (0.83, 3.63)

0.145

   Prostatectomy Gleason score

  

≤ 6

1.0

ref

7 (3 + 4)

25.04 (3.24, 193.72)

0.002

7 (4 + 3)

31.21 (3.66, 266.07)

0.002

8 to 10

33.31 (4.40, 251.92)

0.0007

PAGE4

  

   PAGE4

0.70 (0.33, 1.49)

0.351

   Prostatectomy Gleason score

  

≤ 6

1.0

ref

7 (3 + 4)

24.53 (3.16, 190.61)

0.002

7 (4 + 3)

32.90 (3.83, 282.99)

0.002

8 to 10

32.73 (4.32, 248.21)

0.0007

PBK

  

   PBK

1.40 (0.72, 2.73)

0.321

   Prostatectomy Gleason score

  

≤ 6

1.0

ref

7 (3 + 4)

26.41 (3.42, 203.76)

0.002

7 (4 + 3)

36.04 (4.27, 304.10)

0.001

8 to 10

33.30 (4.40, 252.02)

0.0007

TTK

  

   TTK

1.27 (0.67, 2.42)

0.470

   Prostatectomy Gleason score

  

≤ 6

1.0

ref

7 (3 + 4)

25.56 (3.31, 197.50)

0.002

7 (4 + 3)

38.46 (4.59, 322.31)

0.0008

8 to 10

33.55 (4.44, 253.06)

0.0007

  1. CTAs, Cancer/Testis Antigens; HR, hazard ratio; CI, confidence interval
  2. * CTAs were dichotomized at the median of the value normalized to actin in the non-recurrent group. Hazard ratios represent comparison of values greater than or equal to the median vs. values less than the median.