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Table 3 IHC Expression of Her2 and He3 in Primary Tumors, Paired Metastatic Carcinomas and Recurrent HNSCC

From: Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma

  Primary (n = 387) Metastatic (n = 20) Recurrent (n = 17) P value
Her2 (membranous)     
   Negative 283 (73.1) 11 (55.0) 10 (58.8) 0.104
   Positive 104 (26.9) 9 (45.0) 7 (41.2)  
Her3 (membranous)     
   Negative 353 (91.2) 14 (70.0) 17 (100) 0.003
   Positive 34 (8.8) 6 (30.0) 0 (0)  
Her3 (cytoplasmic)     
   Negative 87 (22.5) 6 (30.0) 3 (17.6) 0.649
   Positive 300 (77.5) 14 (70.0) 14 (82.4)