Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model

Table 1 Flow Cytometric Analysis of Adipose-Derived Mesenchymal Stem Cell Surface Markers Prior to (Day1) and Following Cell Culture (Day 14)

Surface markers	Day 1	Day 14	p-value†
CD31+	22.0 ± 3.5	19.3 ± 6.8	0.563
CD34+	14.1 ± 7.8	15.1 ± 14.9	0.844
KDR+	19.7 ± 2.5	17.4 ± 8.2	0.438
C-kit+	3.13 ± 1.80	2.40 ± 1.24	0.563
Sca-1+	3.22 ± 1.49	2.72 ± 2.10	0.688
VEGF+	14.3 ± 5.2	14.7 ± 8.7	1.0
vWF+	15.9 ± 7.6	15.9 ± 7.1	1.0
CD26+‡	18.0 ± 3.7	4.7 ± 4.4	0.031
CD45+¶	14.1 ± 12.5	11.6 ± 12.0	0.844
CD271+	18.4 ± 5.7	16.6 ± 7.6	0.688
CD29+	23.7 ± 8.7	91.4 ± 7.1	0.031
CD90+	35.2 ± 5.8	88.1 ± 10.9	0.031

Data are expressed as %.
n = 6 in each experimental study.
† by Wilcoxon signed rank test for paired data.
‡ Dipeptidyl peptidase IV (DPP-IV)/CD26 indicates a cell surface glycoprotein.
¶ Leukocyte common antigen.
KDR = Kinase insert domain receptor; VEGF = vascular endothelial growth factor; vWF = von Willebrand Factor.

ISSN: 1479-5876