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Figure 3 | Journal of Translational Medicine

Figure 3

From: Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model

Figure 3

Analysis of mRNA Expressions of IL-1β, TNF-α, MMP-9, eNOS, IL-10, Adiponectin, HO-1, NQO 1, GR, GPx, Caspase 3, Bax, Bcl-2 and ET-1 in Lung Parenchyma after IR Injury. Real-time quantitative PCR for gene expression (n = 8). (A) Interleukin (IL)-1β mRNA expression. *p < 0.04 between the indicated groups. (B) Tumor necrosis factor (TNF)-α mRNA expression. *p < 0.05 between the indicated groups. (C) Matrix metalloproteinase (MMP)-9 mRNA expression. *p < 0.04 between the indicated groups. (D) Endothelial nitric oxide synthase (eNOS) mRNA expression. *p < 0.04 between the indicated groups. (E) IL-10 mRNA expression. *p < 0.05 between the indicated groups. (F) Adiponectin mRNA expression. *p < 0.04 between the indicated groups. (G) Heme oxygenase (HO)-1 mRNA expression. *p < 0.03 between the indicated groups. (H) NAD(P)H quinone oxidoreductase (NQO)-1 mRNA expression. *p < 0.02 between the indicated groups. (I) Glutathione reductase (GR) mRNA expression. *p = 0.01 between the indicated groups. (J) Glutathione peroxidase (GPx) mRNA expression. *p < 0.03 between the indicated groups. (K) Caspase 3 mRNA expression. *p < 0.03 between the indicated groups. (L) Bax mRNA expression. *p < 0.03 between the indicated groups. (M) Bcl-2 mRNA expression. *p < 0.02 between the indicated groups. (N) Endothelin (ET)-1 mRNA expression. *p < 0.03 between the indicated groups. Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test).

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