Figure 6

Impact of conditioned medium treatment on mRNA expression of angiogenic and apoptotic factors in left ventricular myocardium. Real-time PCR showing significantly lower mRNA expressions of (A)SDF-1α, (B)VEGF, (C) endothelial nitric oxide synthase (eNOS), and (D) Bcl-2 in LV myocardium in Group IV (AMI treated by fresh medium) than in other groups (p < 0.03) (n = 6 in each group). Note also remarkably higher gene expressions of (E) Bax and (F) caspase-3 in Group IV than in other groups (p < 0.01).