Comparisons of different organ samples. A) Normal and tissue samples from the three organs (breast, lung and cervix) were obtained and prepared as described. 10 μg of protein were loaded for multiplex cathepsin zymography, and a representative zymogram is shown and cropped for clarity. B) Cathepsin K data was normalized by maximum cathepsin K activity value for each organ and represented by the box and whisker plot. For box and whisker plots, the top and bottom of the box represent the 75th and 25th quartile, and whiskers +1.5 SD and -1.5 SD, respectively.