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Table 1 Endpoints.

From: Rituximab is effective in the treatment of nephritis in lupus patients, refractory to conventional immunosuppressive therapy

 

Baseline

24th weeks

Final Visit

Urinary Sediment (%)

37

9.5**

2.2*

24-hour urine protein (gr/24h)

1.2 ± 2.01

0.34 ± 0.58**

0.22 ± 0.38**

C3 (mg/dl)

78.17 ± 31.08

91.3 ± 31.4**

101.4 ± 30.8*

C4 (mg/dl)

12.52 ± 7.95

16.31 ± 7.51**

19.16 ± 8.74*

Anti-DNA (UI)

34.6 (4.85-70.07)

26.1 (2.12-52.5)

13 (3.9-34)**

SLEDAI

14.5 (7.75-22.25)

4 (2-6)*

2 (0-4)*

Physician´s Global Assessment (PGA)

2.75 (2.0-3.0)

0.0 (0.0-1.0)*

0.0 (0.0-1.0)*

  1. *p < 0,0005 respect to baseline.
  2. **p < 0.05 respect to baseline.