Skip to main content

Table 1 The expressions of Oct4 and Sox2 and their relationships with clinicopathological characteristics.

From: Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma

Features No. patients OCT4 P a SOX2 P a
   High Low   High Low  
Gender       
   Female 1 0 1 - 1 0 -
   Male 84 14 70   66 18  
Age (years)b       
   <60 41 7 34 0.885 35 6 0.154
   ≥60 44 7 37   32 12  
Histological grade       
   Well 34 5 29 0.572 28 6 0.030
   Moderately 39 8 31   33 6  
   Poorly 12 1 11   6 6  
SCCAc (ng/ml)       
   ≤ 1 43 8 35 0.348 34 9 0.794
   > 1 21 2 19   16 5  
TSGFd (ng/ml)       
   ≤ 70 33 4 29 0.298 24 9 0.230
   > 70 22 5 17   19 3  
T Stage       
   1~2 21 3 18 0.756 16 5 0.734
   3~4 64 11 53   51 13  
Cervical lymph node metastasis      
   Positive 19 7 12 0.007 16 3 0.514
   Negative 66 7 59   51 15  
TNM Stage       
   I~II 7 1 6 0.871 4 3 0.143
   III~IV 78 13 65   63 15  
Treatment Typee        
   L + N 7 5 2 - 5 2 -
   L + N+ R 4 1 3   3 1  
   L + N + C 4 1 3   3 1  
   L + N + R + C 6 0 6   2 4  
   N + R 2 0 2   1 1  
   N + R + C 6 2 4   4 2  
   R 3 1 2   2 1  
   R + C 21 2 19   20 1  
   C 20 1 19   17 3  
No treatment or tracheotomy 12 1 11   10 2  
  1. a Chi-square test
  2. b Patients were divided according to the median values of age.
  3. c SCCA, Squamous Cell Carcinoma Antigen
  4. d TSGF, Tumor Supplied Group of Factor
  5. e L = Laryngectomy, N = Neck dissection, R = Radiotherapy, C = Chemotherapy