Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma

Table 1 The expressions of Oct4 and Sox2 and their relationships with clinicopathological characteristics.

Features	No. patients	OCT4		P ^a	SOX2		P ^a
		High	Low		High	Low
Gender
Female	1	0	1	-	1	0	-
Male	84	14	70		66	18
Age (years)^b
<60	41	7	34	0.885	35	6	0.154
≥60	44	7	37		32	12
Histological grade
Well	34	5	29	0.572	28	6	0.030
Moderately	39	8	31		33	6
Poorly	12	1	11		6	6
SCCA^c (ng/ml)
≤ 1	43	8	35	0.348	34	9	0.794
> 1	21	2	19		16	5
TSGF^d (ng/ml)
≤ 70	33	4	29	0.298	24	9	0.230
> 70	22	5	17		19	3
T Stage
1~2	21	3	18	0.756	16	5	0.734
3~4	64	11	53		51	13
Cervical lymph node metastasis
Positive	19	7	12	0.007	16	3	0.514
Negative	66	7	59		51	15
TNM Stage
I~II	7	1	6	0.871	4	3	0.143
III~IV	78	13	65		63	15
Treatment Type^e
L + N	7	5	2	-	5	2	-
L + N+ R	4	1	3		3	1
L + N + C	4	1	3		3	1
L + N + R + C	6	0	6		2	4
N + R	2	0	2		1	1
N + R + C	6	2	4		4	2
R	3	1	2		2	1
R + C	21	2	19		20	1
C	20	1	19		17	3
No treatment or tracheotomy	12	1	11		10	2

ISSN: 1479-5876