Table 2 Adverse Events by Dose Level
Grade 1 Adverse Event | N (%) | 2.5 μg | 25 μg | 100 μg |
|---|---|---|---|---|
Number of patients | 36 | 11 | 16 | 9 |
Nausea | 8 (22) | 2 (18) | 3 (19) | 3 (33) |
Fatigue | 7 (19) | 3 (27) | 2* (12) | 2 (22) |
Headache | 7 (19) | 3 (27) | 2 (12) | 2 (22) |
Constipation | 5 (14) | 2 (18) | 2 (12) | 1 (11) |
Asthenia | 4 (11) | 1 (9) | 1 (6) | 2 (22) |
Pyrexia | 4 (11) | 1 (9) | 1 (6) | 1 (11) |
Visual change | 3 (8) | 1** (6) | 2** (12) | |
Zoster reactivation | 1 (3) | 1 (11) |