Table 2 Summarized Body Weight, Heart Weight, Left Lung Weight and Heart Function in Studied Animals

Initial body weight (g)

328 ± 15.9

323 ± 11.8

323 ± 12.6

317 ± 24.3

325 ± 25.8

0.792

Final body weight (g)

450.0 ± 35.7

468.9 ± 26.4

476.5 ± 25.9

446.0 ± 29.9

465.7 ± 59.0

0.498

Final left lung weight (g)

1.70^a ± 0.09

2.01^b ± 0.15

1.76^a ± 0.16

1.78^a ± 0..21

1.78^a ± 0.08

0.0009

Final heart weight (g)

1.46^a ± 0.11

1.80^b ± 0.24

1.55^a,b ± 0.24

1.51^a,b ± 0.28

1.42^a ± 0.26

0.023

Day 0 LVEF (%)

79.3 ± 2.0

79.3 ± 3.5

80.9 ± 2.3

79.3 ± 3.2

80.9 ± 4.7

0.744

Day-30 LVEF (%)

79.8^a ± 2.5

72.1^b ± 1.7

74.8^a,b ± 3.2

75.9^a,b ± 5.0

78.7^a ± 4.0

0.0005

Day-90 LVEF (%)

79.1^a ± 3.3

70.2^b ± 2.3

74.3^a,b ± 0.6

74.5^a,b± 3.8

78.6^a,b ± 3.0

< 0.0001

FASBP on day 90, mmHg

122 ± 26

116 ± 21

109 ± 19

103 ± 22

108 ± 21

0.213