RFA might affect the expression of HGF and IL-6 in liver and tumor tissues. A, Concentration of HGF; B, Concentration of IL-6. Liver tissues represented the normal tissues from the same liver which was treated with RFA. Data were expressed as means ± SD of three independent experiments. (*P < 0.05, groups I, II and III vs. control group. #P < 0.05, group I vs. groups II and III, by one-way ANOVA and Newman-Keuls test).