Table 3 Mean (± Standard deviation) interventricular septum, posterior wall thickness, left ventricular wall thickness, age at the diagnostis and body mass index values, and frequency of cases with affected relatives, according to the AT1R genotype in the 205 HCM-patients without sarcomeric mutations, the 40 patients with a sarcomeric mutation, and the 145 patients with hypertensive LVH
IVS (mm) | PWT (mm) | LVWT (mm) | Age (years) | BMI | Familial HCM# | |
|---|---|---|---|---|---|---|
HCM-No mutation 1 | ||||||
CC (n = 27) | 21 ± 4 | 13 ± 3 | 34 ± 5 | 49 ± 18 | 26 ± 5 | 10 (37%) |
AC (n = 94) | 21 ± 5 | 13 ± 4 | 33 ± 4 | 46 ± 18 | 27 ± 4 | 40 (43%) |
AA (n = 84) | 19 ± 5 | 13 ± 4 | 32 ± 4 | 48 ± 16 | 27 ± 5 | 25 (30%) |
HCM-Mutation 2 | ||||||
CC (n = 5) | 23 ± 4 | 16 ± 3 | 39 ± 4 | 38 ± 4 | 21 ± 4 | 4 (80%) |
AC (n = 14) | 22 ± 5 | 14 ± 5 | 35 ± 5 | 36 ± 5 | 21 ± 5 | 12 (86%) |
AA (n = 21) | 18 ± 5 | 14 ± 4 | 31 ± 5 | 45 ± 5 | 20 ± 5 | 14 (67%) |
Hypertensive-LVH | ||||||
CC (n = 13) | 16 ± 4 | 10 ± 5 | 25 ± 5 | 60 ± 8 | 28 ± 2 | ND |
AC (n = 60) | 16 ± 3 | 9 ± 4 | 25 ± 4 | 58 ± 7 | 27 ± 2 | ND |
AA (n = 72) | 15 ± 2 | 10 ± 5 | 24 ± 4 | 59 ± 9 | 28 ± 3 | ND |