Figure 2
From: Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity
Differentially expressed genes in LPS-stimulated IRAK4-deficient monocytes downstream of NFκB. Using the open-source bioinformatics visualization software Cytoscape [31] gene expression in LPS-stimulated, IRAK4-deficient monocytes was overlayed on the TLR4 signal transduction pathway downstream of NFκB. Gene names are given in the left panel and gene expression in the right panel. The relative expression of the gene in IRAK4-deficient monocytes is depicted by the colour of the nodes on the protein map; green nodes indicate lower expression and red nodes indicate higher expression in IRAK4-deficient monocytes relative to that in a control pool of monocytes.