Figure 5

Tumour cell growth and regression. Rabbits were injected i.d. with a single dose of non-syngeneic VX2T tumour rabbit cells (107 cells in 200 μl of PBS-), containing the complete genome of CRPV. Tumour size was measured every 6 days with callipers and the volume estimated by the formula width × length × (width + length)/2. The tumour sizes are given for each vaccinated and control (FPwt-injected) animals. All of the rabbits showed a tumour growth up to day 6 post challenge, which was followed by a regression, similar in rabbits vaccinated with the recombinant or FPwt viruses.