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Figure 5 | Journal of Translational Medicine

Figure 5

From: Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits

Figure 5

Tumour cell growth and regression. Rabbits were injected i.d. with a single dose of non-syngeneic VX2T tumour rabbit cells (107 cells in 200 μl of PBS-), containing the complete genome of CRPV. Tumour size was measured every 6 days with callipers and the volume estimated by the formula width × length × (width + length)/2. The tumour sizes are given for each vaccinated and control (FPwt-injected) animals. All of the rabbits showed a tumour growth up to day 6 post challenge, which was followed by a regression, similar in rabbits vaccinated with the recombinant or FPwt viruses.

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