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Table 3 Multivariate analysis for Progression Free Survival

From: Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab

Variables

Entire Population 101 patients

K-ras Population 61 patients

 

HR (CI 95%)

p value

HR (CI 95%)

p value

Increasd EGFR-GCN: no vs yes

1.84 (1.07 - 3.15)

0.03

2.20 (1.03 -- 4.70)

0.04

Number of Lines: II-III vs I

2.20 (1.25 - 3.89)

0.01

4.60 (1.87 -- 11.31)

0.001

EGFR score: 0-1 vs 2-3

2.27 (1.35 - 3.82)

0.002

1.99 (0.89 -- 4.44)

0.09

k-ras mut vs wt

-

-

2.14 (0.97 -- 4.73)

0.06

  1. Mut: mutant; wt: wild-type