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Table 3 Multivariate analysis for Progression Free Survival

From: Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab

Variables Entire Population 101 patients K-ras Population 61 patients
  HR (CI 95%) p value HR (CI 95%) p value
Increasd EGFR-GCN: no vs yes 1.84 (1.07 - 3.15) 0.03 2.20 (1.03 -- 4.70) 0.04
Number of Lines: II-III vs I 2.20 (1.25 - 3.89) 0.01 4.60 (1.87 -- 11.31) 0.001
EGFR score: 0-1 vs 2-3 2.27 (1.35 - 3.82) 0.002 1.99 (0.89 -- 4.44) 0.09
k-ras mut vs wt - - 2.14 (0.97 -- 4.73) 0.06
  1. Mut: mutant; wt: wild-type