Figure 6

Kaplan-Meier curves of overall NPC patient survival. A, Five-year overall survival rates were 54% for patients whose NPC tumors showed high levels of LMP1 (n = 141), and 68% in patients with low LMP1 (n = 83). A significant difference was seen in overall survival rate between the groups (p = 0.020). B, Five-year overall survival rates were 55% in patients with NPC tumors with high p-mTOR expression (n = 109), and 62% in patients with low p-mTOR (n = 114). No significant difference was observed between the groups (p = 0.311). C, Five-year overall survival rates were 49% for patients with NPC tumors with high p-P70S6K expression (n = 106), and 69% for patients with low p-P70S6K expression (n = 118). A significant difference was observed between groups (p = 0.049). D, Five-year overall survival rates were 49% for patients whose NPC tumors showed high p-4EBP1 expression (n = 128), and 71% for patients with low levels of p-4EBP1 (n = 95). A significant difference was seen in the overall survival rate between the two groups (p = 0.010).