Table 1 Composition of the vaccines preparations used and anti-HPV16, HPV18, HPV31 and HPV58 neutralizing antibody titers in mice immunized with the different vaccines.
From: Papillomavirus pseudovirions packaged with the L2 gene induce cross-neutralizing antibodies
Group N° |  | Proteins | Gene | Neutralizing titers | ||||
|---|---|---|---|---|---|---|---|---|
Name | L1 | L2 | HPV16 | HPV18 | HPV31 | HPV58 | ||
1 | Saline | - | - | - | - | - | - | - |
2 | DNA L2 (1 μg) | - | - | HPV31 L2Δ | - | - | - | - |
3 | DNA L2 (10 μg) | - | - | HPV31 L2Δ | - | - | - | - |
4 | 31 L1 VLPs | 31 | - | - | - | - | 2,800 | - |
5 | 31 L1L2 VLPs | 31 | 31 | - | - | - | 3,400 | 65 |
6 | PsV31-HEV | 31 | 31 | HEV ORF2 | - | - | 5,198 | 54 |
7 | PsV58-GFP | 58 | 58 | GFP | - | - | 50 | 4,650 |
8 | PsV58-31L2 | 58 | 58 | HPV31 L2Δ | 60 | 400 | 733 | 5,382 |