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Table 5 Mirs Significantly Differentially Expressed Between Pediatric And Young Adult Nevus (Nevus 30) Vs Pediatric And Young Adult Melanoma (Mel 30)

From: Microrna profiling analysis of differences between the melanoma of young adults and older adults

Array A Hsa-miR Name-Assay# FC (NEVUS30/MEL30) Log2(FC) p value FDR (BH) FC Bin
hsa-miR-886-3p-4395305 0.4464 -1.1637 0.0001 0.0289 FC 2.0-4.0
hsa-miR-449a-4373207 0.2143 -2.2223 0.0006 0.0541 FC > 4
hsa-miR-124-4373295 0.2453 -2.0273 0.0011 0.0541 FC > 4
hsa-miR-382-4373019 0.1211 -3.0453 0.0011 0.0541 FC > 4
hsa-miR-301b-4395503 0.2264 -2.1432 0.0012 0.0541 FC > 4
hsa-miR-363-4378090 0.1417 -2.8193 0.0015 0.0577 FC > 4
hsa-miR-22-4373079 0.1349 -2.8895 0.0019 0.0635 FC > 4
hsa-miR-505-4395200 0.2482 -2.0105 0.0028 0.0749 FC > 4
hsa-miR-135a-4373140 0.3156 -1.6640 0.0031 0.0749 FC 2.0-4.0
hsa-miR-125b-4373148 2.0505 1.0360 0.0032 0.0749 FC 2.0-4.0
hsa-miR-518f-4395499 0.3908 -1.3554 0.0193 0.3107 FC 2.0-4.0
hsa-miR-886-5p-4395304 0.3436 -1.5412 0.0212 0.3107 FC 2.0-4.0
hsa-miR-517c-4373264 0.2671 -1.9043 0.0229 0.3107 FC 2.0-4.0
hsa-miR-31-4395390 0.1841 -2.4418 0.0247 0.3107 FC > 4
hsa-miR-542-3p-4378101 0.4443 -1.1704 0.0251 0.3107 FC 2.0-4.0
hsa-miR-449b-4381011 0.4818 -1.0536 0.0251 0.3107 FC 2.0-4.0
hsa-miR-135b-4395372 0.1699 -2.5570 0.0273 0.3107 FC > 4
hsa-miR-212-4373087 0.3822 -1.3875 0.0279 0.3107 FC 2.0-4.0
hsa-miR-15a-4373123 0.2598 -1.9443 0.0281 0.3107 FC 2.0-4.0
hsa-miR-362-3p-4395228 2.5474 1.3490 0.0301 0.3107 FC 2.0-4.0
hsa-miR-21-4373090 0.3731 -1.4224 0.0302 0.3107 FC 2.0-4.0
hsa-miR-134-4373299 0.4606 -1.1185 0.0305 0.3107 FC 2.0-4.0
hsa-miR-379-4373349 0.5984 -0.7408 0.0318 0.3107 FC 1.6-2.0
hsa-miR-301a-4373064 0.4202 -1.2510 0.0319 0.3107 FC 2.0-4.0
hsa-miR-424-4373201 0.2091 -2.2578 0.0332 0.3107 FC > 4
hsa-miR-548b-5p-4395519 0.5227 -0.9359 0.0382 0.3442 FC 1.6-2.0
hsa-miR-211-4373088 5.3696 2.4248 0.0400 0.3443 FC > 4
hsa-miR-494-4395476 0.2695 -1.8915 0.0412 0.3443 FC 2.0-4.0
hsa-miR-519a-4395526 0.4132 -1.2752 0.0458 0.3697 FC 2.0-4.0
Array B Hsa-miR Name-Assay# FC (NEVUS30/MEL30) Log2(FC) p value FDR (BH) FC Bin
hsa-miR-650-4381006 0.1393 -2.8436 0.0000 0.0036 FC > 4
hsa-let-7iSTAR-4395283 4.3578 2.1236 0.0111 0.2768 FC > 4
hsa-miR-572-4381017 0.3278 -1.6091 0.0117 0.2768 FC 2.0-4.0
hsa-miR-135aSTAR-4395343 0.4993 -1.0021 0.0175 0.2768 FC 2.0-4.0
hsa-miR-768-3p-4395188 1.5165 0.6008 0.0181 0.2768 FC 1.2-1.6
hsa-miR-604-4380973 0.3778 -1.4043 0.0188 0.2768 FC 2.0-4.0
hsa-miR-223STAR-4395209 0.1451 -2.7853 0.0200 0.2768 FC > 4
hsa-miR-639-4380987 0.5274 -0.9230 0.0284 0.3442 FC 1.6-2.0
hsa-miR-214STAR-4395404 0.6008 -0.7349 0.0438 0.4602 FC 1.6-2.0
hsa-miR-409-3p-4395443 0.5134 -0.9619 0.0474 0.4602 FC 1.6-2.0
  1. Array A: TLDA panel A (377 functionally defined microRNAs) array B: TLDA panel B (290 MicroRNAs whose function is not yet completely defined) TLDA A and B totaled 667 microRNA assays. FC: fold change; Pvalue student T test ≤ 0.05; FDR: false discovery rate; FC bin: Range of fold change. MirRs in bold font were found to be significantly differentially expressed between the two groups by the relative quantification (ABqPCR software-Analysis I) based method and by Class Comparison (BRB tools-Analysis II) based on absolute CT values normalized to endogenous control MammU6 (see materials and methods). N/A: not applicable.