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Table 1 Comparative study of the percentage of viability among Caco-2, SW-480 and HT-29 cell lines at different time of treatments.

From: TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status

Time

Treatment

Caco-2

SW-480

HT-29

P value

24 H

NT

0.72 ± 0.07

1.30 ± 0.23

0.80 ± 0.17

0.012

 

OXA

0.51 0.09

1.22 ± 0.11

0.58 ± 0.05

< 0.001

 

CETU

0.67 ± 0.12

1.27 ± 0.20

0.59 ± 0.16

0.004

 

OXA+ CETU

0.29 ± 0.05

1.03 ± 0.28

0.57 ± 0.10

0.006

48 H

NT

1.29 ± 0.24

2.36 ± 0.13

1.22 ± 0.07

<0.001

 

OXA

0.73 ± 0.15

1.31 ± 0.22

1.08 ± 0.05

0.012

 

CETU

1.03 ± 0.11

1.88 ± 0.15

1.28 ± 0.41

0.017

 

OXA+ CETU

0.91 ± 0.06

1.32 ± 0.13

1.05 ± 0.20

0.032

72 H

NT

3.48 ± 0.02

3.23 ± 0.40

2.02 ± 0.11

0.017

 

OXA

1.44 ± 0.13

1.19 ± 0.25

0.89 ± 0.07

0.100

 

CETU

3.03 ± 0.15

3.13 ± 0.11

2.43 ± 0.31

0.079

 

OXA+ CETU

1.55 ± 0.15

1.26 ± 0.03

1.00 ± 0.08

0.025