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Figure 6 | Journal of Translational Medicine

Figure 6

From: Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

Figure 6

Heterotopic tumors treated by H19-DTA-P4-DTA. Heterotopic bladder tumors treated with H19-DTA-P4-DTA vector (black) or with H19-Luc-P4-Luc control vector (white) were excised and the ex-vivo tumors volume were measured (A) and weighted (B). C-D: Necrosis of heterotopic tumors treated with H19-DTA-P4-DTA: Hematoxylin Eosin (HE) staining (×10) of representative sections of tumors treated with H19-Luc-P4-Luc (C), or with H19-DTA-P4-DTA (D). The necrotic areas are indicated by arrows (D). Inserts are macroscopic photographs of the heterotopic tumors.

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Journal of Translational Medicine

ISSN: 1479-5876

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