Figure 2

Expansion of CIK cells, NK cells and CD8⁺ T cells in cultures supplemented with TG. The absolute number of CD3⁺CD8⁺ T cells, NK cells (CD3^-CD16⁺CD56⁺) and CIK cells (CD3⁺CD16⁺CD56⁺) was estimated weekly after the provision of either αCD3 mAb (panel A) or TG (panel B) to the cultures. Cumulative results from 10 experiments performed with 10 different PBMC preparations are expressed as median and inter-quartile range. *denotes a statistically significant difference (p < 0.05) when comparing cell numbers in TG-containing cultures with those in cultures nurtured with an equal concentration of αCD3 mAb.