Figure 3From: Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaqueEffect of NSC23766 on aggregation of platelets in blood and PRP stimulated with ADP. (A) Blood (with or without aspirin) or (B) PRP (with or without aspirin) was pre-treated with 300 μM NSC23766 for 5 min whilst stirring at 37°C before stimulation with ADP (5 μM). Aggregation values of PRP are % of maximal aggregation induced by collagen (5 μg/ml). Values are mean ± SD (n = 4). * p < 0.05.Back to article page