DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy

Table 3 Accuracy, sensitivity, specificity, positive predictive value, and negative predictive value according to Polη IHC counting percent in predicting chemotherapy response to FOLFOX or XELOX regimen

Tumor cell positive percent, cut off	Specificity	Sensitivity	PPV	NPV	Accuracy
1%	0.419	0.889	0.308	0.929	0.525
2%	0.500	0.889	0.340	0.940	0.588
3%	0.645	0.889	0.421	0.952	0.700
4%	0.823	0.889	0.593	0.962	0.838
5%	0.887	0.889	0.696	0.965	0.888
6%	0.887	0.778	0.667	0.932	0.863
7%	0.978	0.667	0.705	0.904	0.863
8%	0	0.389	1.000	0.849	0.863
9%	0	0.111	1.000	0.795	0.800

ISSN: 1479-5876