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Table 3 Accuracy, sensitivity, specificity, positive predictive value, and negative predictive value according to Polη IHC counting percent in predicting chemotherapy response to FOLFOX or XELOX regimen

From: DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy

Tumor cell positive percent, cut off Specificity Sensitivity PPV NPV Accuracy
1% 0.419 0.889 0.308 0.929 0.525
2% 0.500 0.889 0.340 0.940 0.588
3% 0.645 0.889 0.421 0.952 0.700
4% 0.823 0.889 0.593 0.962 0.838
5% 0.887 0.889 0.696 0.965 0.888
6% 0.887 0.778 0.667 0.932 0.863
7% 0.978 0.667 0.705 0.904 0.863
8% 0 0.389 1.000 0.849 0.863
9% 0 0.111 1.000 0.795 0.800
  1. PPV, positive predictive value; NPV, negative predictive value.