Figure 4
GH1 therapy upregulated adiponectin and enhanced hepatic adipoR2 mRNA expression in alcohol-fed mice. (A) Serum HMW adiponectin concentrations. (B) Relative mRNA levels of adipoR1. (C) Relative mRNA levels of adipoR2. (D) Relative adipose tissue mRNA levels of adiponectin, TNFα, SIRT1 and FOXO1. AdipoR1: adiponectin receptor 1; AdipoR2: adiponectin receptor 2; FOXO1: forkhead transcription factor O 1; HMW adiponectin: high molecular weight adiponectin; SIRT1, sirtuin 1; TNFα, tumor necrosis factor-α. n = 6 mice per group. Means without a common letter differ at P< 0.05 vs. control group.