Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study

Table 4 Logistic Regression Analysis of Morbidity and Mortality With Stepwise Selection

	gene	p value	R		gene	p value	R		gene	p value	R
DVD				1Y-mortality				6M-mortality
POD0	IL-6	< 0.0001	0.787	POD0	IL-6	0.016	0.69	POD0	VWF	< 0.0001	0.893
days of ICU stay					VWF	0.021			IL-6	< 0.0001
POD0	IL-6	< 0.0001	0.813		TGF-β1	0.009		30D-mortality
days of SIRS				POD1	PDGFA	0.009	0.71	POD0	VWF	< 0.0001	1.000
POD0	IL-6	< 0.0001	0.738		ERG1	0.004			NAMPT	< 0.0001
Pneumonia					HMGB1	0.012		POD5	HMGB1	< 0.0001	0.993
POD3	IL-6	0.021	0.442	POD3	NAMPT	0.007	0.63		MUC1	0.002
PaO ₂ /FiO ₂ ratio					MUC1	0.012		POD14	NAMPT	< 0.0001	1.000
POD1	MMP9	0.034	0.409	POD14	ERG1	0.0016	0.59		PDGFA	< 0.0001
SOFA score					NAMPT	0.0016			CRP	0.015
POD1	TGF-β1	0.005	0.528

N.A: no applicable; N.S.: not significant. R: correlation coefficient.
DVD: duration of ventilator dependence. Independence variables are MMP9, CRP (pre, POD1, peak), ERG, HMGB1, MUC1, PBEF, PDGFA, TGF-β1, TNF-α, VWF, IL-6, Sivelestat, PMX, anesthesia and operation time.

ISSN: 1479-5876