Table 1 Cytokines in Plasma of Female CFS Patients Compared to Female Healthy Controls
From: Plasma cytokines in women with chronic fatigue syndrome
CYTOKINEB | TYPE | CFS CASES N = 40 | CONTROLS N = 59 | % DIFFERENCE IN MEDIAN VALUESC | KRUSKAL-WALLIS | |
|---|---|---|---|---|---|---|
|  |  |  |  |  | χ 2 | P |
TNFα | Pro-inflammatory | 7.3 (3.4 - 22.6) | 6.4 (4.5 - 38.3) | + 14 | 0.0 | .949 |
LTα | Pro-inflammatory | 7.5 (4.5 - 38.3) | 2.1 (4.5 - 12.4) | + 257 | 20.4 | .000 |
IL-6 | Pro-inflammatory | 6.4 (3.8 - 14.4) | 3.2 (2.1 - 5.9) | +100 | 15.1 | .000 |
IL-1α | Pro-inflammatory | 3.2 (1.7 - 4.4) | 2.3 (0.9 - 3.9) | + 39 | 4.1 | .044 |
IL-1β | Pro-inflammatory | 13.4 (4.5 - 38.3) | 6.2 (4.2 - 38.3) | + 100 | 4.2 | .041 |
IFNγ | TH1 | 3.1 (0.1 - 11.8) | 2.6 (1.2 - 10.6) | + 19 | 0.5 | .467 |
IL-2 | TH1 | 2.3 (1.4 - 5.4) | 2.5 (2.1 - 3.5) | - 8 | 0.6 | .420 |
IL-12 | TH1 | 4.4 (2.4 - 7.3) | 2.0 (1.7 - 2.5) | + 120 | 18.8 | .000 |
IL-15 | TH1 | 13.5 (7.0 - 23.6) | 27.4 (19.7 - 49.4) | - 51 | 15.0 | .000 |
IL-17 | TH17 | 3.8 (0.8 - 7.2) | 2.9 (1.9 - 6.7) | + 31 | 0.1 | .785 |
IL-23 | TH17 | 82.(70.3 - 113) | 101.7 (45.0 - 375.6) | - 16 | 0.8 | .814 |
IL-4 | TH2 | 1.7 (0.9 - 4.3) | 0.5 (.03 - 1.1) | + 240 | 20.7 | .000 |
IL-5 | TH2 | 7.4 (6.3 - 10.0) | 3.8 (3.2 - 5.6) | + 95 | 33.6 | .000 |
IL-10 | Anti-inflammatory | 3.3 (2.1 - 5.6) | 3.6 (2.2 - 6.4) | - 9 | 0.1 | .748 |
IL-13 | Anti-inflammatory | 1.7 (1.2 - 2.1) | 2.0 (1.9 - 2.1) | -15 | 9.6 | .002 |
IL-8 (CXCL8) | NK cell attracting | 9. (5.0 - 15.8) | 15.4 (11.5 - 22.2) | - 42 | 9.7 | .002 |