Skip to main content

Table 1 Cytokines in Plasma of Female CFS Patients Compared to Female Healthy Controls

From: Plasma cytokines in women with chronic fatigue syndrome

CYTOKINEB TYPE CFS CASES
N = 40
CONTROLS
N = 59
% DIFFERENCE IN MEDIAN VALUESC KRUSKAL-WALLIS
      χ 2 P
TNFα Pro-inflammatory 7.3 (3.4 - 22.6) 6.4 (4.5 - 38.3) + 14 0.0 .949
LTα Pro-inflammatory 7.5 (4.5 - 38.3) 2.1 (4.5 - 12.4) + 257 20.4 .000
IL-6 Pro-inflammatory 6.4 (3.8 - 14.4) 3.2 (2.1 - 5.9) +100 15.1 .000
IL-1α Pro-inflammatory 3.2 (1.7 - 4.4) 2.3 (0.9 - 3.9) + 39 4.1 .044
IL-1β Pro-inflammatory 13.4 (4.5 - 38.3) 6.2 (4.2 - 38.3) + 100 4.2 .041
IFNγ TH1 3.1 (0.1 - 11.8) 2.6 (1.2 - 10.6) + 19 0.5 .467
IL-2 TH1 2.3 (1.4 - 5.4) 2.5 (2.1 - 3.5) - 8 0.6 .420
IL-12 TH1 4.4 (2.4 - 7.3) 2.0 (1.7 - 2.5) + 120 18.8 .000
IL-15 TH1 13.5 (7.0 - 23.6) 27.4 (19.7 - 49.4) - 51 15.0 .000
IL-17 TH17 3.8 (0.8 - 7.2) 2.9 (1.9 - 6.7) + 31 0.1 .785
IL-23 TH17 82.(70.3 - 113) 101.7 (45.0 - 375.6) - 16 0.8 .814
IL-4 TH2 1.7 (0.9 - 4.3) 0.5 (.03 - 1.1) + 240 20.7 .000
IL-5 TH2 7.4 (6.3 - 10.0) 3.8 (3.2 - 5.6) + 95 33.6 .000
IL-10 Anti-inflammatory 3.3 (2.1 - 5.6) 3.6 (2.2 - 6.4) - 9 0.1 .748
IL-13 Anti-inflammatory 1.7 (1.2 - 2.1) 2.0 (1.9 - 2.1) -15 9.6 .002
IL-8
(CXCL8)
NK cell attracting 9. (5.0 - 15.8) 15.4 (11.5 - 22.2) - 42 9.7 .002
  1. a Values are expressed as medians. Values in parentheses are 25th and 75th percentiles.
  2. b Cytokines determined as pg/ml.
  3. c Percent differences were calculated by using the normal controls as a reference; the + or - sign indicates the direction of change.