Figure 4

Julolidine analogue of 3a-G1 presents constant regulatory activity on CD4⁺ T cell proliferation. a) Detailed structure of the julolidine analogue of 3a-G1. Dashed frame highlights the julolidine moiety that has replaced one of the azabisphosphonate claws of the parental 3a-G1 dendrimer. b) The replacement of one azabisphosphonate branch by the julolidine unit does not alter the capacity of the fluorescent 3a-G1 analogue to inhibit CD4⁺ T cell proliferation under anti-CD3/CD28 stimulation.