From: Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance
Karyotype
% of cases, rangea
Prognosis
Known and/or putative involved genes
13q14.3 loss
14–40
goodb
mir-16-1; mir-15a
11q22-23 loss
10–32
bad
ATM
trisomy 12
11–18
intermediate
CLLU1
17p13.1 loss
3–27
TP53