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Table 1 Intrinsic factors with prognostic relevance

From: Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance

Karyotype % of cases, rangea Prognosis Known and/or putative involved genes
13q14.3 loss 14–40 goodb mir-16-1; mir-15a
11q22-23 loss 10–32 bad ATM
trisomy 12 11–18 intermediate CLLU1
17p13.1 loss 3–27 bad TP53
  1. aAccording to [30];
  2. bIf the sole genetic aberration.