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Table 1 Intrinsic factors with prognostic relevance

From: Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance

Karyotype

% of cases, rangea

Prognosis

Known and/or putative involved genes

13q14.3 loss

14–40

goodb

mir-16-1; mir-15a

11q22-23 loss

10–32

bad

ATM

trisomy 12

11–18

intermediate

CLLU1

17p13.1 loss

3–27

bad

TP53

  1. aAccording to [30];
  2. bIf the sole genetic aberration.