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Table 2 Summary of the effect of Panax ginseng extract (PGSE) on TNF-α regulated genes

From: Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells

Mock

TNF

PGSE+TNF

PGSE

Gene symbol

Description

1.0

53.55

5.61

1.35

CXCL10

Chemokine (C-X-C motif) ligand 10

1.0

13.04

11.03

0.82

TNFAIP3

TNF-α-induced protein 3

1.0

12.40

12.15

1.93

CXCL2

Chemokine (C-X-C motif) ligand 2

1.0

12.28

8.64

1.14

NFKBIA

NK-κB inhibitor, alpha

1.0

11.17

9.75

0.88

TNFAIP3

TNF-α-induced protein 3

1.0

7.47

6.04

0.99

IER3

Immediate early response 3

1.0

7.21

2.35

0.86

GPR84

G protein-coupled receptor 84

1.0

7.18

4.90

1.20

NFKBIZ

NF-κB inhibitor, zeta

1.0

6.22

4.37

0.62

PDE4B

Phosphodiesterase 4B

1.0

6.06

13.38

5.39

IL8

Interleukin 8

1.0

6.05

2.70

0.83

TNFAIP6

TNF-α-induced protein 6

1.0

4.12

1.65

1.10

TNFAIP6

TNF-α-induced protein 6

1.0

3.73

11.23

4.38

IL8

Homo sapiens IL8 C-terminal variant

1.0

3.11

2.23

0.81

CCL3

Chemokine (C-C motif) ligand 3

1.0

2.55

0.64

0.70

CXCL11

Chemokine (C-X-C motif) ligand 11

1.0

2.30

2.51

1.35

CCL2

Chemokine (C-C motif) ligand 2

1.0

1.00

0.50

0.49

IL18R1

Interleukin 18 receptor 1

1.0

0.98

2.12

2.05

IL1B

Interleukin 1, beta

1.0

0.92

2.36

1.83

IL1B

Interleukin 1, beta