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Figure 8 | Journal of Translational Medicine

Figure 8

From: Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life

Figure 8

Gd concentration maps over time of larger anterior brain RG-2 gliomas and smaller posterior brain RG-2 gliomas within a representative rat of the Normal Saline, Met-Lys-BK, and Labradimil groups. (A) Anterior brain gliomas: tumor volumes, 153 mm3 (NS), 127 mm3 (Met-Lys-BK), 102 mm3 (Labradimil); (B) Posterior brain gliomas: tumor volumes, 14 mm3 (NS), 51 mm3 (Met-Lys-BK), 35 mm3 (Labradimil). Note: Residual contrast in tissue prior to the 2nd Gd-DTPA bolus.

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