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Table 1 Baseline Demographics of Patient Groups

From: Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis

  ICU
Sepsis
ICU
Controls
Healthy
Controls
ANOVA
P-value
Number of Subjects 24 25 21  
Age, mean (SD) 54.0 (17.1) 56.1 (15.9) 46.5 (6.1) 0.13
Male Gender, n (%) 15 (58) 13 (52) 17 (80) 0.49
Black or African
American race, n (%)
22 (92)† 14 (56) 15 (71) 0.02
White race, n (%) 2 (8) 11 (44) 5 (29) 0.02
HIV infected, n (%) 4 (17) 0 0 0.02
Diabetes, n (%) 9 (38) 6 (24) 2 (10) 0.09
Cardiovascular disease, n (%) 14 (58) 17 (68) 8 (38) 0.12
Malignancy, n (%) 2 (8) 0 1 (5) 0.35
APACHE Score,
mean (SD)
25.7 (7.4) 11.8 (5.4) N/A <0.0001
SOFA, mean (SD) 11.9 (4.0) 5.3 (3.2) N/A <0.0001
Albumin, mean (SD) mg/dL 2.0 (2.6)‡ 2.1 (0.7)# 4.0 (0.5) <0.0001
Prothrombin Time
(PT) mean (SD)*
16.7 (2.9) 15.3 (2.8) 16.8 (3.9) 0.98
Partial thromboplastin time
(PTT) mean (SD)*
48.8 (37.0) 35.1 (5.3) 34.8 (1.7) 0.05
INR, mean (SD) 1.6 (0.4)†‡ 1.2 (0.3) 1.3 (0.4) 0.0009
AST, mean (SD),
units/L
87.0 (131) 49.9 (48) 33.0 (26) 0.09
ALT, mean (SD),
units/L
43.6 (44) 51.3 (75) 25.4 (17) 0.24
BUN, mean (SD),
mg/dL
52.4 (28) †‡ 27.8 (17)# 12.6 (5.1) <0.0001
Creatinine, mean (SD),
mg/dL
4.0 (3.2) †‡ 1.1 (0.7) 1.0 (1.1) <0.0001
Hemoglobin, mean
(SD) g/dL
9.8 (2.0)‡ 10.6 (1.2)# 13.8 (1.1) <0.0001
White Blood Count
(cells/μL)
17.3 (13)‡ 15.2 (7.1)# 6.5 (1.9) <0.0002
  1. * in seconds
  2. Tukey-Kramer Multiple Comparisons Test
  3. † P < 0.05, ICU Sepsis vs ICU Controls
  4. ‡ P < 0.05, ICU Sepsis vs Healthy Controls
  5. # P < 0.05, ICU Control vs Healthy Controls
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