Table 1 Baseline Demographics of Patient Groups

Number of Subjects

24

25

21

Age, mean (SD)

54.0 (17.1)

56.1 (15.9)

46.5 (6.1)

0.13

Male Gender, n (%)

15 (58)

13 (52)

17 (80)

0.49

Black or African

American race, n (%)

22 (92)†

14 (56)

15 (71)

0.02

White race, n (%)

2 (8)

11 (44)

5 (29)

0.02

HIV infected, n (%)

4 (17)

0

0

0.02

Diabetes, n (%)

9 (38)

6 (24)

2 (10)

0.09

Cardiovascular disease, n (%)

14 (58)

17 (68)

8 (38)

0.12

Malignancy, n (%)

2 (8)

0

1 (5)

0.35

APACHE Score,

mean (SD)

25.7 (7.4)

11.8 (5.4)

N/A

<0.0001

SOFA, mean (SD)

11.9 (4.0)

5.3 (3.2)

N/A

<0.0001

Albumin, mean (SD) mg/dL

2.0 (2.6)‡

2.1 (0.7)#

4.0 (0.5)

<0.0001

Prothrombin Time

(PT) mean (SD)*

16.7 (2.9)

15.3 (2.8)

16.8 (3.9)

0.98

Partial thromboplastin time

(PTT) mean (SD)*

48.8 (37.0)

35.1 (5.3)

34.8 (1.7)

0.05

INR, mean (SD)

1.6 (0.4)†‡

1.2 (0.3)

1.3 (0.4)

0.0009

AST, mean (SD),

units/L

87.0 (131)

49.9 (48)

33.0 (26)

0.09

ALT, mean (SD),

units/L

43.6 (44)

51.3 (75)

25.4 (17)

0.24

BUN, mean (SD),

mg/dL

52.4 (28) †‡

27.8 (17)#

12.6 (5.1)

<0.0001

Creatinine, mean (SD),

mg/dL

4.0 (3.2) †‡

1.1 (0.7)

1.0 (1.1)

<0.0001

Hemoglobin, mean

(SD) g/dL

9.8 (2.0)‡

10.6 (1.2)#

13.8 (1.1)

<0.0001

White Blood Count

(cells/μL)

17.3 (13)‡

15.2 (7.1)#

6.5 (1.9)

<0.0002