Figure 3
(A) HepG2 variants were pre-treated for 24 h with 200 μM RES and RES concentrations were detected in the cytoplasm by HPLC. (B) – Values for individual variants. (C) – Res concentration in the cytoplasm of individual HepG2 cells after 24 h pre-treatment with 200 μM RES. Each bar represents the mean ± S.E.M. of three independent experiments. (D) Cytoplasmic RES concentration in HepG2 variants after 10-6~10-4 M/L Diethylstilbestrol (DES) plus RES measured by HPLC. (E) Individual variant values. (F) Mean ± S.E.M. values of three individual experiments. *, statistically significant differences between experimental variant and HepG2 cell control, p < 0.05.