Figure 3From: Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCsA. Maximal tetramer response (DCT vs DCTI). Time course of tetramer response to vaccination in a patient (N001) who generated the highest level of tetramer+CD8+T cells after 2 courses (V2), compared with baseline (V0). B. Flowcytometry of peak tetramer response: Tetramer flowcytometry plots for N001 at V0 and V2, 150,000 events were acquired and analysed. C. Representative tetramer response (DCT vs DCTI): Time course of tetramer responses to vaccination in a representative patient (N010) who generated equivalent tetramer+CD8+T cell responses to DCT and DCTI. D. Flowcytometry of representative tetramer response: Tetramer flowcytometry plots for N010 at V0, V1 and V2. MAGE-3 was used as the control, non-TAAg;150,000 events were acquired and analysed.Back to article page