Figure 7
Cytostatic and cytotoxic effects of CD437, LND and BA treatment on ADF cells. CD437, BA and LND exert both cytostatic and cytotoxic effects on ADF cells. (A) Mitotic index analysis. Each value has been normalized versus the respective vehicle treated control to which an arbitrary value of 100% as been assigned. Each point is the mean of two independent experiments performed in triplicate. The mitotic indexes of drug treated samples were compared with those of the vehicle treated controls using the unpaired t-test *P < 0.05; **P < 0.01. (B) Calcein AM staining assay. Each bar indicates the percentage of live and death cells and is the mean of two experiments performed in triplicate. The number of live cells counted in the drug treated samples was compared to that of the vehicle treated controls using the unpaired t-test. *P < 0.05; **P < 0.01; ***P < 0.001.