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Table 2 The Expression of TGFβ downstream targets between the weak and strong TGFβ response groups in Glioblastomas

From: Heterogeneous activation of the TGFβ pathway in glioblastomas identified by gene expression-based classification using TGFβ-responsive genes

  

Freijie et al

Nutt et al

Gene Title

Gene Symbol

p Value

Fold Change

p Value

Fold Change

collagen, type I, alpha 1

COL1A1

8.55E-09

6.68

0.018768

2.93

collagen, type I, alpha 2

COL1A2

4.13E-10

4.36

7.10E-05

10.38

collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)

COL3A1

6.22E-09

5.61

0.002025

5.30

collagen, type IV, alpha 1

COL4A1

7.71E-09

8.38

0.000171

5.48

collagen, type IV, alpha 2

COL4A2

4.75E-09

5.20

4.19E-05

7.69

collagen, type V, alpha 1

COL5A1

4.35E-10

3.82

0.002531

-1.11

collagen, type V, alpha 2

COL5A2

3.52E-09

3.95

5.43E-07

5.14

collagen, type VI, alpha 1

COL6A1

6.40E-07

3.09

2.48E-05

4.95

collagen, type VI, alpha 2

COL6A2

4.04E-11

6.79

4.24E-05

25.45

Collagen, type VIII, alpha 1

COL8A1

1.94E-08

4.52

0.122094

1.27

fibronectin 1

FN1

2.10E-07

2.43

5.45E-05

3.77

serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

SERPINE1

1.54E-09

5.69

0.000334

10.83

TGFB-induced factor (TALE family homeobox)

TGIF

1.71E-05

1.83

1.63E-06

3.41

thrombospondin 1

THBS1

2.17E-08

4.28

0.301818

1.29

tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)

TIMP1

1.22E-15

6.46

4.19E-06

23.22

vascular endothelial growth factor

VEGF

5.23E-06

3.32

5.72E-06

10.90