Figure 8
Cytotoxic activities of AMACR peptide-specific CTLs against HLA-A24-positive AMACR-expressing prostate cancer cell lines. AMACR peptide-specific CTLs were examined for the cytotoxic activity against HLA-A24-positive AMACR-expressing prostate cancer lines, LNCaP-A*2402 and DU145-A*2402, which were stable HLA-A*2402-transfectants of LNCaP and DU145, respectively. The cytotoxicity was assessed by 51Cr release assay at the indicated effector/target ratios.