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Figure 2 | Journal of Translational Medicine

Figure 2

From: NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols

Figure 2

Effect of NCX-4040 and/or cisplatin on the viability of A2780 WT and A2780 cDDP cell lines. Cells were incubated with 25 μM of NCX-4040 for 6 h, then with cisplatin for 1 h (IC67 dose for A2780 WT) with a 24 h follow up time. Cell viability was evaluated using MTT assay. Data represent mean ± SD obtained from 4 independent experiments and expressed as a percentage of the control cells treated with vehicle (1% DMSO). *p < 0.01 versus Control group. **p < 0.05 versus cDDP or NCX-4040 group.

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