Table 3 Summary of staining and detailed patient data for the ovarian tumor tissue microarray stained with anti-Aurora-A antibody.
From: Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
Tumor Type | Stage | Grade | No. of Patients | Age at Surgery | Survival (Months) | TMA Score | % Cells Aurora-A Positive |
|---|---|---|---|---|---|---|---|
Benign | - | - | 7 | 65 (10) | - | 2.5 (0.5) | 80 (17) |
Carcinoma No Chemotherapy | I | 3 | 1 | 47 | - | 2.9 | 84 |
| Â | II | 3 | 1 | 61 | - | 2 | 44 |
| Â | III | 2 | 1 | 45 | - | 2.4 | 75 |
| Â | Â | 3 | 3 | 61 (14) | - | 2.4 (0.7) | 65 (20) |
| Â | IV | 3 | 1 | 74 | - | 1.3 | 30 |
Carcinoma With Chemotherapy | III | 1 | 1 | 55 | 53 | 1.8 | 59 |
| Â | Â | 2 | 9 | 63 (13) | 29 (16) | 2 (0.6) | 70 (15) |
| Â | Â | 3 | 9 | 61 (8) | 33 (6) | 2.3 (0.5) | 79 (14) |
| Â | IV | 2 | 1 | 51 | 62 | 1.8 | 48 |
| Â | Â | 3 | 1 | 72 | 22 | 2 | 78 |