Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers

Table 2 Selection of significantly differentially expressed genes in adenocarcinomas focusing on cell structure, cell adhesion and oncogenesis.

Gene Symbol	Gene Name	Fold Change AC vs. NT	q-value
cell structure
COL1A1	collagen, type I, alpha 1	7.98	1.22
KRT7	keratin 7	5.11	0.53
PLS3	plastin 3	2.43	0.53
TMSB10	thymosin, beta 10	2.01	0.89
ARPC1B	actin related protein 2/3 complex, 1B	2.38	1.22
TUBA3	tubulin, alpha 3	0.39	1.22
TUBB2	tubulin, beta 2	0.33	0.53
KRT15	keratin 15	0.06	0.53
KRT5	keratin 5	0.05	0.53
cell adhesion
ICAM1	intercellular adhesion molecule 1	5.80	0.89
ITGB2	integrin, ί-2	2.48	1.22
ITGA3	integrin α-3	2.02	1.53
DSG3	desmoglein 3	0.48	0.53
DSC3	desmocollin 3	0.32	0.53
oncogenesis
SERPINH1	serine (or cysteine) proteinase inhibitor, clade H	3.27	0.89
PNMA2	paraneoplastic antigen MA2	3.13	0.89
MSH3	mutS homolog 3	0.44	0.53
MYB	v-myb Avian Myeloblastosis viral oncogene homolog	0.39	0.53
RABL2B	rab-like 2B	0.34	0.53
RABL2A	rab-like 2A	0.27	0.53

ISSN: 1479-5876