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Table 7 Comparison of fold changes between Pegaysy and Peg-intron at day 3

From: Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment

Gene Symbol

Probe Set ID

Gene Title

Pegasys1

PegIntron2

IFI27

202411_at

interferon, alpha-inducible protein 27

46.6

73.3

SIGLEC1

219519_s_at

sialic acid binding Ig-like lectin 1, sialoadhesin

15.7

27.1

CCL2

216598_s_at

chemokine (C-C motif) ligand 2

15.1

13.4

RSAD2

213797_at

radical S-adenosyl methionine domain containing 2

11.7

12.8

IFIT1

203153_at

interferon-induced protein with tetratricopeptide repeats 1

11.3

12.2

HESX1

211267_at

HESX homeobox 1

14.7

11.5

IFI44L

204439_at

interferon-induced protein 44-like

6.5

10.1

USP18

219211_at

ubiquitin specific peptidase 18///similar to ubiquitin specific peptidase 18

5.6

7.4

IFIT3

204747_at

interferon-induced protein with tetratricopeptide repeats 3

7.6

7.1

IFI44

214059_at

Interferon-induced protein 44

4.8

7.1

ISG15

205483_s_at

ISG15 ubiquitin-like modifier

6.2

6.8

SIGLEC1

44673_at

sialic acid binding Ig-like lectin 1, sialoadhesin

5.5

6.4

LAMP3

205569_at

lysosomal-associated membrane protein 3

4.1

6.0

IFI44

214453_s_at

interferon-induced protein 44

4.5

6.0

HERC6

219352_at

hect domain and RLD 6

4.2

5.9

MX1

202086_at

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

4.3

5.0

SERPING1

200986_at

serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)

4.0

4.9

OASL

205660_at

2'-5'-oligoadenylate synthetase-like

4.9

4.6

HERC5

219863_at

hect domain and RLD 5

4.4

4.5

OAS3

218400_at

2'-5'-oligoadenylate synthetase 3, 100 kDa

4.1

4.5

  1. 1Fold-changes in Virahep C study []
  2. 2Fold-changes in this study.