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Table 7 Comparison of fold changes between Pegaysy and Peg-intron at day 3

From: Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment

Gene Symbol Probe Set ID Gene Title Pegasys1 PegIntron2
IFI27 202411_at interferon, alpha-inducible protein 27 46.6 73.3
SIGLEC1 219519_s_at sialic acid binding Ig-like lectin 1, sialoadhesin 15.7 27.1
CCL2 216598_s_at chemokine (C-C motif) ligand 2 15.1 13.4
RSAD2 213797_at radical S-adenosyl methionine domain containing 2 11.7 12.8
IFIT1 203153_at interferon-induced protein with tetratricopeptide repeats 1 11.3 12.2
HESX1 211267_at HESX homeobox 1 14.7 11.5
IFI44L 204439_at interferon-induced protein 44-like 6.5 10.1
USP18 219211_at ubiquitin specific peptidase 18///similar to ubiquitin specific peptidase 18 5.6 7.4
IFIT3 204747_at interferon-induced protein with tetratricopeptide repeats 3 7.6 7.1
IFI44 214059_at Interferon-induced protein 44 4.8 7.1
ISG15 205483_s_at ISG15 ubiquitin-like modifier 6.2 6.8
SIGLEC1 44673_at sialic acid binding Ig-like lectin 1, sialoadhesin 5.5 6.4
LAMP3 205569_at lysosomal-associated membrane protein 3 4.1 6.0
IFI44 214453_s_at interferon-induced protein 44 4.5 6.0
HERC6 219352_at hect domain and RLD 6 4.2 5.9
MX1 202086_at myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 4.3 5.0
SERPING1 200986_at serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) 4.0 4.9
OASL 205660_at 2'-5'-oligoadenylate synthetase-like 4.9 4.6
HERC5 219863_at hect domain and RLD 5 4.4 4.5
OAS3 218400_at 2'-5'-oligoadenylate synthetase 3, 100 kDa 4.1 4.5
  1. 1Fold-changes in Virahep C study []
  2. 2Fold-changes in this study.