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Figure 3 | Journal of Translational Medicine

Figure 3

From: Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin

Figure 3

Silencing of ABCC2 by siRNA increased the sensitivity of cisplatin in CNE2 without changing the cellular viability. (A) Cellular growth curve. The cell growth viability was assessed by MTT method for 7 days. (B) Modulation of sensitivity against cisplatin for CNE2 cells. MTT method was used to determined the IC50 value of cisplatin to CNE2 cells treated with ABCC2-shRNA construct (ShABCC2-1 and shABCC2-2) and ABCC2-shRNA negative construct (ShABCC2-). Data were expressed as mean ± SEM value. N = 3, * P < 0.05 vs. CNE2.

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Journal of Translational Medicine

ISSN: 1479-5876

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