Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients

Table 3 Post MI Subjects with Aberrant Platelet Response to Aspirin

	# of subjects
Non-Compliant
1. Prescribed daily aspirin	16
2. Protocol directive not to take Aspirin for 7 days	45
3. Protocol directive not to take NANSAIDs for 7 days	1
Protocol Compliant
<1 S.D. decrease in Net Aspirin Inhibition	5
Total	67

93% (62 of 67) of aberrant platelet responses to aspirin were due to non-compliance. Among compliant post MI subjects 3% may be classified as aspirin resistant.

ISSN: 1479-5876