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Table 5 MILANO analysis for oncogenes and tumor suppressor genes

From: Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China

Gene symbol Role1 Fold difference2 (NPC/NP) Description Map Location
MIF Candidate oncogene 10.72 macrophage migration inhibitory factor (glycosylation-inhibiting factor) 22q11.23
BIRC5 Oncogene 6.62 baculoviral IAP repeat-containing 5 (survivin) 17q25
PTTG1 Proto-oncogene 7.35 pituitary tumor-transforming 1 5q35.1
CCND2 Proto-oncogene 20.15 cyclin D2 12p13
ATM Tumor suppressor 0.27 ataxia telangiectasia mutated (includes complementation groups A, C and D) 11q22-q23
FOXO1A Tumor suppressor 0.20 forkhead box O1A (rhabdomyosarcoma) 13q14.1
TGFBR2 Tumor suppressor 0.19 transforming growth factor, beta receptor II 3p22
PRKAR1A Tumor suppressor 0.17 protein kinase, cAMP-dependent, regulatory, type I, alpha 17q23-q24
KLF5 Tumor suppressor 0.17 Kruppel-like factor 5 (intestinal) 13q22.1
PDCD4 Tumor suppressor 0.10 programmed cell death 4 (neoplastic transformation inhibitor) 10q24
  1. 1 Role: functions identified by MILANO
  2. 2 Fold difference: extracted from our microarray data.