Figure 6From: A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrientAnti-pruretic effects between Zangrado and a commercial hemorrhoid crème. Subcutaneous 5-HT administration (black column, n = 11) evoked a significant scratching response over saline (control, *** p < 0.001). This scratching response was significantly attenuated by either topical administration of Preparation H (Prep H, purple column, * p < 0.01, n = 7) or Zangrado (red column, ** p < 0.001, n = 10), when applied immediately after the administration of 5-HT.Back to article page