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Table 2 Genotype and allele frequencies by race*

From: Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation

Gene Polymorphism Genotype White, n (%) Black, n (%)
ADRB1 Ser49Gly Ser/Ser 399 (76) 49 (47)
   Ser/Gly 121 (23) 49 (47)
   Gly/Gly 3 (1) 6 (6)
   MAF 0.12 0.29
  Arg389Gly Arg/Arg 265 (51) 37 (36)
   Arg/Gly 215 (41) 54 (52)
   Gly/Gly 41 (8) 13 (12)
   MAF 0.29 0.38
ADRB2 Gly16Arg Gly/Gly 175 (33) 18 (17)
   Gly/Arg 263 (50) 56 (54)
   Arg/Arg 86 (16) 30 (29)
   MAF 0.42 0.56
  Gln27Glu Gln/Gln 193 (37) 74 (71)
   Gln/Glu 253 (48) 29 (28)
   Glu/Glu 77 (15) 1 (1)
   MAF 0.39 0.15
ADRB3 Trp64Arg Trp/Trp 439 (84) 81 (79)
   Trp/Arg 78 (15) 21 (20)
   Arg/Arg 3 (1) 1 (1)
   MAF 0.08 0.11
ADRA1A Arg347Cys Arg/Arg 163 (31) 6 (6)
   Arg/Cys 270 (52) 43 (41)
   Cys/Cys 91 (17) 55 (53)
   MAF 0.43 0.74
GNAS 393 T > C T/T 139 (27) 60 (58)
   T/C 254 (49) 42 (40)
   C/C 130 (25) 2 (2)
   MAF 0.49 0.22
GNB3 825 C > T C/C 280 (53) 7 (7)
   C/T 210 (40) 30 (29)
   T/T 34 (7) 67 (64)
   MAF 0.27 0.79
  1. Abbreviations: MAF, minor allele frequency
  2. *all P < 0.05 for genotype frequency by race