Table 2 Genotype and allele frequencies by race*
Gene | Polymorphism | Genotype | White, n (%) | Black, n (%) |
|---|---|---|---|---|
ADRB1 | Ser49Gly | Ser/Ser | 399 (76) | 49 (47) |
| Â | Â | Ser/Gly | 121 (23) | 49 (47) |
| Â | Â | Gly/Gly | 3 (1) | 6 (6) |
| Â | Â | MAF | 0.12 | 0.29 |
| Â | Arg389Gly | Arg/Arg | 265 (51) | 37 (36) |
| Â | Â | Arg/Gly | 215 (41) | 54 (52) |
| Â | Â | Gly/Gly | 41 (8) | 13 (12) |
| Â | Â | MAF | 0.29 | 0.38 |
ADRB2 | Gly16Arg | Gly/Gly | 175 (33) | 18 (17) |
| Â | Â | Gly/Arg | 263 (50) | 56 (54) |
| Â | Â | Arg/Arg | 86 (16) | 30 (29) |
| Â | Â | MAF | 0.42 | 0.56 |
| Â | Gln27Glu | Gln/Gln | 193 (37) | 74 (71) |
| Â | Â | Gln/Glu | 253 (48) | 29 (28) |
| Â | Â | Glu/Glu | 77 (15) | 1 (1) |
| Â | Â | MAF | 0.39 | 0.15 |
ADRB3 | Trp64Arg | Trp/Trp | 439 (84) | 81 (79) |
| Â | Â | Trp/Arg | 78 (15) | 21 (20) |
| Â | Â | Arg/Arg | 3 (1) | 1 (1) |
| Â | Â | MAF | 0.08 | 0.11 |
ADRA1A | Arg347Cys | Arg/Arg | 163 (31) | 6 (6) |
| Â | Â | Arg/Cys | 270 (52) | 43 (41) |
| Â | Â | Cys/Cys | 91 (17) | 55 (53) |
| Â | Â | MAF | 0.43 | 0.74 |
GNAS | 393 T > C | T/T | 139 (27) | 60 (58) |
| Â | Â | T/C | 254 (49) | 42 (40) |
| Â | Â | C/C | 130 (25) | 2 (2) |
| Â | Â | MAF | 0.49 | 0.22 |
GNB3 | 825 C > T | C/C | 280 (53) | 7 (7) |
| Â | Â | C/T | 210 (40) | 30 (29) |
| Â | Â | T/T | 34 (7) | 67 (64) |
| Â | Â | MAF | 0.27 | 0.79 |