Skip to main content

Table 4 CD8 Annexin V Levels at Baseline and 6 Years.

From: CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV

% Annexin V levels (mean ± SD) Baseline (mean ± SD) 6 Years (mean ± SD)
  CD4 (cells/mm3) CD8 (cells/mm3) CD4:CD8 Ratio CD4 (cells/mm3) CD8 (cells/mm3) CD4:CD8 Ratio
Low 2.2 ± 2.1 625 ± 221 967 ± 386 0.76 ± 0.4 1209 ± 164 915 ± 308 1.55 ± 0.9
High 17.0 ± 6.0 527 ± 132 1234 ± 660 0.56 ± 0.36 754 ± 320 1172 ± 456 0.76 ± 0.4
p-value p = 0.331 p = 0.374 p = 0.327 p = 0.001 p = 0.240 p = 0.038
  1. CD4 values, CD8 values, and CD4:CD8 ratios were recorded at baseline and 6 years for the low and high apoptosis groups. At baseline, a parametric t test showed no significance between low and high CD8 apoptosis levels for CD4, CD8 or CD4:CD8 ratios. However, after 6 years, a significant difference was observed between the high and low annexin groups with respect to CD4 values and CD4:CD8 ratios with p values of ≥ 0.001 and ≥ 0.037. CD8 was not significantly different at any time point.