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Table 4 CD8 Annexin V Levels at Baseline and 6 Years.

From: CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV

% Annexin V levels (mean ± SD)

Baseline (mean ± SD)

6 Years (mean ± SD)

 

CD4 (cells/mm3)

CD8 (cells/mm3)

CD4:CD8 Ratio

CD4 (cells/mm3)

CD8 (cells/mm3)

CD4:CD8 Ratio

Low 2.2 ± 2.1

625 ± 221

967 ± 386

0.76 ± 0.4

1209 ± 164

915 ± 308

1.55 ± 0.9

High 17.0 ± 6.0

527 ± 132

1234 ± 660

0.56 ± 0.36

754 ± 320

1172 ± 456

0.76 ± 0.4

p-value

p = 0.331

p = 0.374

p = 0.327

p = 0.001

p = 0.240

p = 0.038

  1. CD4 values, CD8 values, and CD4:CD8 ratios were recorded at baseline and 6 years for the low and high apoptosis groups. At baseline, a parametric t test showed no significance between low and high CD8 apoptosis levels for CD4, CD8 or CD4:CD8 ratios. However, after 6 years, a significant difference was observed between the high and low annexin groups with respect to CD4 values and CD4:CD8 ratios with p values of ≥ 0.001 and ≥ 0.037. CD8 was not significantly different at any time point.
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Journal of Translational Medicine

ISSN: 1479-5876

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